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There are several matches for 'probable hydrolase'.
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3231 matches
showing page 1 of 162
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organism
protein
1)
Homo sapiens
PNKD -
Probable
hydrolase
PNKD;
Probable
hydrolase
that plays an aggravative role in the development of cardiac hypertrophy via activation of the NF-kappa-B signaling pathway; Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
[a.k.a. MR-1S, UPI00015B3BEE, AAH36457.1]
2)
Homo sapiens
MINDY4 -
Probable
ubiquitin carboxyl-terminal
hydrolase
MINDY-4;
Probable
hydrolase
that can remove 'Lys-48'-linked conjugated ubiquitin from proteins; Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
[a.k.a. 84182, BC098569, Q71AZ7]
3)
Homo sapiens
SERHL2 - Serine
hydrolase
-like protein 2;
Probable
serine
hydrolase
. May be related to cell muscle hypertrophy.
[a.k.a. CCDS14037.1, ENST00000437469, ENST00000335879]
4)
Homo sapiens
HINT2 - Histidine triad nucleotide-binding protein 2, mitochondrial;
Hydrolase
probably
involved in steroid biosynthesis. May play a role in apoptosis. Has adenosine phosphoramidase activity. Belongs to the HINT family.
[a.k.a. Histidine triad nucleotide binding protein 2, ENSG00000137133, ENST00000474848.6]
5)
Homo sapiens
GLB1L - Beta-galactosidase-1-like protein;
Probable
glycosyl
hydrolase
.
[a.k.a. MGC10771, AK055098, UPI000013E2A6]
6)
Homo sapiens
USP9Y -
Probable
ubiquitin carboxyl-terminal
hydrolase
FAF-Y; May function as a ubiquitin-protein or polyubiquitin
hydrolase
involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Monoubiquitination of SMAD4 hampers its ability to form a stable co [...]
[a.k.a. USP9Y_HUMAN, NX_O00507, ENST00000382939]
7)
Homo sapiens
USP9X -
Probable
ubiquitin carboxyl-terminal
hydrolase
FAF-X; Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Specifically hydrolyzes 'Lys-48'-, 'Lys-29'- and 'Lys-33'- linked polyubiquitins chains. Essential component of TGF-beta/BMP signaling cascade. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Deubiquitinat [...]
[a.k.a. R-HSA-170834, ENST00000462850, XP_005272733.1]
8)
Homo sapiens
GBE1 - 1,4-alpha-glucan-branching enzyme; Required for normal glycogen accumulation. The alpha 1-6 branches of glycogen play an important role in increasing the solubility of the molecule (
Probable
); Belongs to the glycosyl
hydrolase
13 family. GlgB subfamily.
[a.k.a. HPA038075, GBE1-206, ENST00000484687.1]
9)
Homo sapiens
ACOT6 - Putative acyl-coenzyme A thioesterase 6; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. It is unclear if human acyl-coenzyme A thioesterase 6/ACOT6 has an acyl-CoA thioesterase (
Probable
); Belongs to the C/M/P thioester
hydrolase
family.
[a.k.a. R-HSA-556833, UPI00021CF0DA, Q3I5F7]
10)
Homo sapiens
UPB1 - Beta-ureidopropionase; Catalyzes a late step in pyrimidine degradation. Converts N-carbamoyl-beta-alanine (3-ureidopropanoate) into beta-alanine, ammonia and carbon dioxide. Likewise, converts N-carbamoyl-beta- aminoisobutyrate (3-ureidoisobutyrate) into beta-aminoisobutyrate, ammonia and carbon dioxide (
Probable
). Belongs to the carbon-nitrogen
hydrolase
superfamily. BUP family.
[a.k.a. AF169555, AF169556, UPI0000401FD2]
11)
Homo sapiens
UCHL1 - Ubiquitin carboxyl-terminal
hydrolase
isozyme L1; Ubiquitin-protein
hydrolase
involved both in the processing of ubiquitin precursors and of ubiquitinated proteins (
Probable
). This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes (By similarity). The homodimer may have ATP-independent ubiquitin ligase activity.
[a.k.a. AAY40923.1, NM_004181, UCHL1-205]
12)
Homo sapiens
NUDT17 - Nucleoside diphosphate-linked moiety X motif 17;
Probably
mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix
hydrolase
family.
[a.k.a. XM_011509260.2, UPI0000418EB1, AL160282]
13)
Homo sapiens
NUDT18 - 8-oxo-dGDP phosphatase NUDT18; Mediates the hydrolysis of oxidized nucleoside diphosphate derivatives. Hydrolyzes 8-oxo-7,8-dihydroguanine (8-oxo-Gua)-containing deoxyribo- and ribonucleoside diphosphates to the monophosphates. Hydrolyzes 8-oxo-dGDP and 8-oxo-GDP with the same efficiencies. Hydrolyzes also 8-OH-dADP and 2-OH-dADP. Exhibited no or minimal hydrolysis activity against 8-oxo-dGTP, 8-oxo-GTP, dGTP, GTP, dGDP and GDP.
Probably
removes oxidized guanine nucleotides from both the DNA and RNA precursor pools; Belongs to the Nudix
hydrolase
family.
[a.k.a. XP_011542952.1, UPI0000074169, OTTHUMG00000163774]
14)
Homo sapiens
DPEP3 - Dipeptidase 3;
Probable
metalloprotease which hydrolyzes cystinyl-bis- glycine. May be involved in meiosis (By similarity); Belongs to the metallo-dependent
hydrolases
superfamily. Peptidase M19 family.
[a.k.a. EC 3.4.13.19, R-HSA-556833, NM_022357.3]
15)
Homo sapiens
EDEM1 - ER degradation-enhancing alpha-mannosidase-like protein 1; Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan- independent manner,
probably
by forming a complex with SEL1L. It has low mannosidase activity, catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2. Belongs to the glycosyl
hydrolase
47 family.
[a.k.a. ENST00000256497, R-HSA-901042, 9695]
16)
Homo sapiens
USP20 - Ubiquitin carboxyl-terminal
hydrolase
20; Deubiquitinating enzyme involved in beta-2 adrenergic receptor (ADRB2) recycling. Acts as a regulator of G-protein coupled receptor (GPCR) signaling by mediating the deubiquitination beta-2 adrenergic receptor (ADRB2). Plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutively binding ADRB2, mediating deubiquitination of ADRB2 and inhibiting lysosomal trafficking of ADRB2. Upon dissociation, it is
probably
transferred to the translocated beta-arrestins, possibly leading to beta-arrestins de [...]
[a.k.a. ENST00000472108, KIAA1003, ENSG00000136878]
17)
Homo sapiens
USP8 - Ubiquitin carboxyl-terminal
hydrolase
8;
Hydrolase
that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation. Converts both 'Lys-48' an 'Lys-63'-linked ubiquitin chains. Catalytic activity is enhanced in the M phase. Involved in cell proliferation. Required to enter into S phase in response to serum stimulation. May regulate T-cell anergy mediated by RNF128 via the formation of a complex containing RNF128 and OTUB1.
Probably
regulates the stability of STAM2 and RASGRF1. Regulates endoso [...]
[a.k.a. UPI00022F8549, R-HSA-6807004, ENSP00000302239]
18)
Mus musculus
Pnkd -
Probable
hydrolase
PNKD;
Probable
hydrolase
that plays an aggravative role in the development of cardiac hypertrophy via activation of the NF-kappa-B signaling pathway.
[a.k.a. AAH58945.1, Paroxysmal nonkinesiogenic dyskinesia protein, ENSMUST00000129219]
19)
Mus musculus
Mindy4 -
Probable
ubiquitin carboxyl-terminal
hydrolase
MINDY-4;
Probable
hydrolase
that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.
[a.k.a. MGI:3583959, ENSMUSP00000061221, Mindy4-202]
20)
Mus musculus
Serhl - Serine
hydrolase
-like protein;
Probable
serine
hydrolase
. May be related to cell muscle hypertrophy.
[a.k.a. Serine hydrolase-like, NP_075964.1, AC133880]
3231 matches
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